For more information on veterinary medication error prevention and analysis, see the FDA Center for Veterinary Medicine webpage. Pharmacies that dispense human drugs for veterinary patients should contact the prescribing veterinarian if there are questions about a prescription, without making assumptions regarding what the veterinarian intended if the prescription does not make sense or is not available (eg, hydrocodone 5 mg). ![]() Cats are 7 to 10 times more susceptible to acetaminophen toxicity than dogs 3 acetaminophen should never be given to cats, even at low doses. Dogs are not the only pets affected by acetaminophen. ![]() 2 Symptoms of acetaminophen toxicity in dogs include brownish-gray colored gums hypothermia jaundice labored breathing swollen face, neck, or limbs vomiting and coma. However, acetaminophen is often avoided in dogs because of the increased risk of toxicity.ĭogs typically experience acetaminophen toxicity when doses exceed 75 mg/kg of body weight, which can lead to serious adverse outcomes, such as permanent liver damage. Thus, the pharmacist assumed that the prescriber was using a shortened name for the combination product with acetaminophen. Hydrocodone as a singular product is available in an extended-release formulation (Zohydro ER and Hyslingla ER) at higher-strength capsules or tablets starting at 10 mg, which cannot be cut or opened. The veterinarian had prescribed hydrocodone 5 mg without realizing that the medication is available only in this strength in combination with other products, such as acetaminophen, homatropine methylbromide, or ibuprofen. Under the Animal Medicinal Drug Use Clarification Act of 1994, 1 the FDA recognizes the professional judgment of veterinarians and permits extra-label drug use, or the use of an approved drug that is not in accordance with the approved labeling, including use in another species at a different dose, frequency, or route or for a different indication.Ī recent report described an error in which hydrocodone and acetaminophen 5 mg/325 mg was dispensed for a dog. ![]() Community pharmacies are increasingly making veterinary medicine a specialty, dispensing both human and veterinary products. The Institute for Safe Medication Practices (ISMP) occasionally receives reports of veterinary medication errors.
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